Cardiology CPT Codes for 2025 + Modifiers

The success of your practice relies heavily on the accuracy of your medical billing. It’s essential to ensure precise processing of claims, using the correct cardiology CPT codes and modifiers. The accuracy of your coding directly influences your potential reimbursement, underscoring the importance of meticulous coding to optimize collections.

Cardiology CPT Code Ranges in 2025

• 0051T – Implantation of an artificial heart system with recipient cardiectomy
• 0052T – Replacement or repair of components of artificial heart system (thoracic unit)
• 0053T – Replacement or repair of components of artificial heart system (excluding thoracic unit)
• 33496 – Repair of non-structural prosthetic valve dysfunction with cardiopulmonary bypass as a separate procedure.
• 33542 – Myocardial resection, such as ventricular aneurysmectomy.
• 33545 – Repair of postinfarction ventricular septal defect, with or without myocardial resection.
• 33548 – Surgical ventricular restoration procedure, which includes prosthetic patch placement when performed.
• 33732 – Correction of cor triatriatum or supravalvular mitral ring through resection of the left atrial membrane.

New CPT Codes for 2025

• 0913T – Percutaneous transcatheter therapeutic drug delivery by intracoronary drug-delivery balloon
• 0914T – Add-on for separate target lesion in intracoronary drug-coated balloon procedures
• 0897T – Noninvasive augmentative arrhythmia analysis derived from computational simulations
• 0898T – Noninvasive determination of absolute myocardial blood flow
• 0902T – QTc interval analysis using augmentative algorithmic ECG

Thoracic Procedures

• 32658 – Surgical thoracoscopy with pericardial clot or foreign body removal
• 32659 – Surgical thoracoscopy with pericardial window creation or partial sac resection for drainage
• 32661 – Surgical thoracoscopy with pericardial cyst, tumor, or mass excision

Pericardial Procedures

• 33020 – Pericardiotomy for clot or foreign body removal (primary procedure)
• 33025 – Creation of pericardial window or partial resection for drainage
• 33030 – Subtotal or complete pericardiectomy without cardiopulmonary bypass
• 33031 – Subtotal or complete pericardiectomy with cardiopulmonary bypass
• 33050 – Removal of pericardial cyst or tumor

Cardiac Tumor Excision and Ablation

• 33120 – Excision of intracardiac tumor with resection using cardiopulmonary bypass
• 33130 – Removal of external cardiac tumor

Cardiac Arrhythmia Ablation

• 33250 – Surgical ablation of supraventricular arrhythmogenic focus or pathway without cardiopulmonary bypass
• 33251 – Surgical ablation of supraventricular arrhythmogenic focus or pathway with cardiopulmonary bypass
• 33254 – Surgical tissue ablation and reconstruction of atria (limited)
• 33255 – Surgical tissue ablation and reconstruction of atria (extensive) without cardiopulmonary bypass
• 33256 – Surgical tissue ablation and reconstruction of atria (extensive) with cardiopulmonary bypass
• 33257 – Surgical tissue ablation and reconstruction of atria (limited) performed concurrently with other cardiac procedures
• 33258 – Surgical tissue ablation and reconstruction of atria (extensive) performed concurrently with other cardiac procedures without cardiopulmonary bypass
• 33259 – Surgical tissue ablation and reconstruction of atria (extensive) performed concurrently with other cardiac procedures with cardiopulmonary bypass
• 33261 – Surgical ablation of ventricular arrhythmogenic focus with cardiopulmonary bypass
• 33265 – Surgical endoscopic tissue ablation and reconstruction of atria (limited) without cardiopulmonary bypass
• 33266 – Surgical endoscopic tissue ablation and reconstruction of atria (extensive) without cardiopulmonary bypass
• 33267 – Open exclusion of left atrial appendage using any method
• 33268 – Open exclusion of left atrial appendage performed concurrently with other sternotomy or thoracotomy procedures using any method
• 33269 – Thoracoscopic exclusion of left atrial appendage using any method

Cardiotomy and Cardiac Wound Repair

• 33300 – Repair of cardiac wound without bypass
• 33305 – Repair of cardiac wound with cardiopulmonary bypass
• 33310 – Exploratory cardiotomy (includes removal of foreign bodies, atrial, or ventricular thrombus) without bypass
• 33315 – Exploratory cardiotomy (includes removal of foreign bodies, atrial, or ventricular thrombus) with cardiopulmonary bypass

Transcatheter Aortic Valve Replacement (TAVR/TAVI)

• 33365 – Transcatheter aortic valve replacement (TAVR/TAVI) with prosthetic valve via transaortic approach
• 33366 – Transcatheter aortic valve replacement (TAVR/TAVI) with prosthetic valve via transapical exposure

Aortic Valve Procedures

• 33390 – Open valvuloplasty of the aortic valve with cardiopulmonary bypass; simple procedure
• 33391 – Open valvuloplasty of the aortic valve with cardiopulmonary bypass; complex procedure
• 33404 – Construction of apical-aortic conduit
• 33405 – Open replacement of aortic valve with prosthetic valve other than homograft or stentless valve using cardiopulmonary bypass
• 33406 – Open replacement of aortic valve with allograft valve (freehand) using cardiopulmonary bypass
• 33410 – Open replacement of aortic valve with stentless tissue valve using cardiopulmonary bypass
• 33411 – Replacement of aortic valve with aortic annulus enlargement, noncoronary sinus
• 33412 – Replacement of aortic valve with transventricular aortic annulus enlargement (Konno procedure)
• 33413 – Replacement of aortic valve by translocation of autologous pulmonary valve with allograft replacement of pulmonary valve (Ross procedure)
• 33414 – Repair of left ventricular outflow tract obstruction by patch enlargement
• 33415 – Resection or incision of subvalvular tissue for discrete subvalvular aortic stenosis
• 33416 – Ventriculomyotomy (-myectomy) for idiopathic hypertrophic subaortic stenosis
• 33417 – Aortoplasty (gusset) for supravalvular stenosis
• 33440 – Aortic valve replacement through the translocation of an autologous pulmonary valve and enlargement of the left ventricular outflow tract.

Mitral Valve Procedures

• 33420 – Mitral valve valvotomy performed on a closed heart.
• 33422 – Mitral valve valvotomy performed on an open heart with cardiopulmonary bypass.
• 33425 – Mitral valve valvuloplasty conducted with cardiopulmonary bypass.
• 33426 – Mitral valve valvuloplasty conducted with cardiopulmonary bypass, including the placement of a prosthetic ring.
• 33427 – Mitral valve valvuloplasty conducted with cardiopulmonary bypass, involving radical reconstruction with or without a ring.
• 33430 – Replacement of the mitral valve with the assistance of cardiopulmonary bypass.

Tricuspid Valve Procedures

• 33460 – Tricuspid valve valvectomy performed with cardiopulmonary bypass.
• 33463 – Tricuspid valve valvuloplasty performed without ring insertion.
• 33464 – Tricuspid valve valvuloplasty performed with ring insertion.
• 33465 – Replacement of the tricuspid valve with the assistance of cardiopulmonary bypass.
• 33468 – Repositioning and plication of the tricuspid valve for Ebstein anomaly.

Pulmonary Valve Procedures

• 33474 – Pulmonary valve valvotomy conducted on an open heart with cardiopulmonary bypass.
• 33475 – Replacement of the pulmonary valve.
• 33476 – Resection of the right ventricle for infundibular stenosis, with or without commissurotomy.
• 33478 – Augmentation of the outflow tract, with or without commissurotomy or infundibular resection.

Ventricular Septal Defect (VSD) Repair

• 33600 – Closure of the atrioventricular valve (mitral or tricuspid) by suture or patch.
• 33602 – Closure of the semilunar valve (aortic or pulmonary) by suture or patch.
• 33608 – Repair of complex cardiac anomaly other than pulmonary atresia with ventricular septal defect by construction or replacement of a conduit.
• 33610 – Surgical enlargement of the ventricular septal defect for repair of complex cardiac anomalies (e.g., single ventricle with subaortic obstruction).
• 33611 – Repair of double outlet right ventricle with intraventricular tunnel repair.
• 33612 – Repair of double outlet right ventricle with intraventricular tunnel repair, including repair of right ventricular outflow tract obstruction.
• 33615 – Closure of atrial septal defect and anastomosis of atria or vena cava to pulmonary artery for repair of complex cardiac anomalies (e.g., tricuspid atresia).
• 33617 – Repair of complex cardiac anomalies (e.g., single ventricle) by modified Fontan procedure.
• 33619 – Repair of single ventricle with aortic outflow obstruction and aortic arch hypoplasia (hypoplastic left heart syndrome) (e.g., Norwood procedure).
• 33641 – Repair of the atrial septal defect, secundum, with or without patch using cardiopulmonary bypass.
• 33645 – Direct or patch closure of sinus venosus, with or without anomalous pulmonary venous drainage.
• 33647 – Repair of atrial septal defect and ventricular septal defect, with direct or patch closure.
• 33660 – Repair of incomplete or partial atrioventricular canal (ostium primum atrial septal defect), with or without atrioventricular valve repair.
• 33665 – Repair of intermediate or transitional atrioventricular canal, with or without atrioventricular valve repair.
• 33670 – Repair of the complete atrioventricular canal, with or without prosthetic valve.
• 33675 – Closure of multiple ventricular septal defects.
• 33676 – Closure of multiple ventricular septal defects, with pulmonary valvotomy or infundibular resection (acyanotic).
• 33677 – Closure of multiple ventricular septal defects, with removal of pulmonary artery band, with or without gusset.
• 33681 – Closure of single ventricular septal defect, with or without patch.
• 33684 – Closure of single ventricular septal defect, with or without a patch, including pulmonary valvotomy or infundibular resection (acyanotic).
• 33688 – Closure of single ventricular septal defect, with or without patch, including removal of pulmonary artery band, with or without gusset.
• 33692 – Complete repair of tetralogy of Fallot without pulmonary atresia.
• 33694 – Comprehensive repair of tetralogy of Fallot without pulmonary atresia, including the use of a transannular patch.
• 33697 – Comprehensive repair of tetralogy of Fallot with pulmonary atresia, involving the creation of a conduit from the right ventricle to the pulmonary artery and closure of the ventricular septal defect.

Sinus of Valsalva Procedures

• 33702 – Surgical correction of sinus of Valsalva fistula with the assistance of cardiopulmonary bypass.
• 33710 – Surgical correction of sinus of Valsalva fistula with cardiopulmonary bypass, combined with repair of a ventricular septal defect.
• 33720 – Surgical repair of sinus of Valsalva aneurysm with the aid of cardiopulmonary bypass.

Atrial Septostomy and Atrial Baffle Procedures

• 33735 – Atrial septectomy or septostomy performed on a closed heart, known as the Blalock-Hanlon type operation.
• 33736 – Atrial septectomy or septostomy conducted on an open heart with the support of cardiopulmonary bypass.

Transposition of Great Arteries Repair

• 33770 – Repair of transposition of the great arteries with ventricular septal defect and subpulmonary stenosis without surgically enlarging the ventricular septal defect.
• 33774 – Correction of transposition of the great arteries through the atrial baffle procedure (e.g., Mustard or Senning type) with cardiopulmonary bypass.
• 33776 – Correction of transposition of the great arteries through the atrial baffle procedure (e.g., Mustard or Senning type) with cardiopulmonary bypass, along with closure of the ventricular septal defect.
• 33780 – Correction of transposition of the great arteries through aortic pulmonary artery reconstruction (e.g., Jatene type) with the closure of the ventricular septal defect.
• 33782 – Aortic root translocation with the repair of the ventricular septal defect and pulmonary stenosis (i.e., Nikaidoh procedure) without reimplantation of coronary ostia.
• 33783 – Aortic root translocation with the repair of the ventricular septal defect and pulmonary stenosis (i.e., Nikaidoh procedure) with reimplantation of one or both coronary ostia.
• 33786 – Total repair of truncus arteriosus, following the Rastelli type operation.

Aortopulmonary Septal Defect Repair

• 33814 – Obliteration of aortopulmonary septal defect with the aid of cardiopulmonary bypass.

Ventricular Assist Device Insertion and Removal

• 33920 – Repair of pulmonary atresia with ventricular septal defect by constructing or replacing a conduit from the right or left ventricle to the pulmonary artery.
• 33975 – Insertion of an extracorporeal ventricular assist device for a single ventricle.
• 33976 – Insertion of an extracorporeal ventricular assist device for biventricular support.
• 33977 – Removal of an extracorporeal ventricular assist device for a single ventricle.
• 33978 – Removal of an extracorporeal ventricular assist device for biventricular support.
• 33979 – Insertion of an implantable intracorporeal ventricular assist device for a single ventricle.
• 33980 – Removal of an implantable intracorporeal ventricular assist device for a single ventricle.

Cardiology Modifiers

Add modifiers where you can to improve the accuracy of billing and reduce the risk of the claim getting denied. The following are recent additions to the list of modifiers:

• 310 – Not vaccinated against COVID-19
• 311 – Partly vaccinated against COVID-19
• 39 – Indicates any other under-immunized status

For informational purposes only.