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Ophthalmology CPT Codes and Modifiers for 2025

Check out the latest CPT codes and modifiers for 2025
Read Time: 4 minutes
Mar 7, 2025

Ophthalmology practices perform a wide variety of services—from routine eye exams and imaging to complex surgical procedures. To ensure your claims are paid promptly and accurately, you need to stay current with CPT codes and modifiers for 2025.

This guide outlines the most commonly used Ophthalmology CPT codes and modifiers, plus coding tips to help your billing team stay compliant and maximize reimbursements.

Evaluation & Management (E/M) Codes

CPT CodeDescription
92002New patient, intermediate eye exam
92004New patient, comprehensive eye exam
92012Established patient, intermediate eye exam
92014Established patient, comprehensive eye exam
99202–99205New patient E/M (levels 2–5)
99212–99215Established patient E/M (levels 2–5)

Diagnostic Testing & Imaging

CPT CodeDescription
92133OCT of optic nerve, unilateral or bilateral
92134OCT of retina, unilateral or bilateral
92083Visual field exam, extended
92201Extended ophthalmoscopy, new patient
92202Extended ophthalmoscopy, established patient
92250Fundus photography
92060Sensorimotor exam
76514B-scan ocular ultrasound
92285External ocular photography

Common Ophthalmic Procedures

CPT CodeDescription
67028Intravitreal injection of medication
65855Laser trabeculoplasty (glaucoma)
66761YAG laser capsulotomy
66984Cataract surgery with IOL
67840Excision of lesion on eyelid
68761Closure of lacrimal punctum by plug
65435Removal of corneal epithelium

Commonly Used Modifiers in Ophthalmology

ModifierDescription
-25Significant, separately identifiable E/M on same day
-50Bilateral procedure
-RT / -LTRight or left eye
-24Unrelated E/M during post-op period
-57Decision for surgery
-79Unrelated procedure during post-op period
-55Post-op care only

Common ICD-10 Codes in Ophthalmology

ICD-10 CodeDescription
H25.13Age-related nuclear cataract, bilateral
H40.11X3Primary open-angle glaucoma, severe stage
H52.13Myopia, bilateral
H53.003Unspecified amblyopia, bilateral
H35.31Nonexudative age-related macular degeneration
H10.9Unspecified conjunctivitis
H43.1Vitreous degeneration

Ophthalmology Coding Tips for 2025

  • Use eye codes or E/M codes appropriately: Choose based on complexity and content of the visit.
  • Include laterality when required: RT/LT modifiers are crucial.
  • Use -25 carefully: Make sure documentation supports billing E/M alongside minor procedures.
  • Watch global periods: Especially after surgeries like cataracts or YAG.

Final Thoughts

Billing in ophthalmology can get complex fast—especially when dealing with imaging, surgical procedures, and post-op rules. Using the correct Ophthalmology CPT codes and modifiers in 2025 helps reduce denials, get paid faster, and keep your practice compliant.

For informational purposes only.