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Pathology CPT Codes for 2023 + Modifiers

Understand the CPT code changes for pathology medical billing
Read Time: 1 minute
Jun 2, 2023

Billing accuracy is essential in everyday medical practices. If your pathology practice’s codes are inaccurate, claims may end up being denied. The better the accuracy, the higher the collection rate. To that end, it’s important to be aware of the latest CPT codes and modifiers.

Pathology CPT Code Ranges for 2023

Here are the pathology CPT code updates for 2023:

  • 81418 – drug metabolism
  • 81441 – inherited bone marrow failure syndromes
  • 81449 – targeted genomic sequence analysis panel, solid organ neoplasm
  • 81451 – targeted genomic sequence analysis panel
  • 81456 – targeted genomic sequence analysis panel, solid organ or hematolymphoid neoplasm or disorder, 51 or greater genes
  • 87468 – infectious agent detection by nucleic acid (DNA or RNA); Anaplasma phagocytophilum, amplified probe technique
  • 87469 – infectious agent detection by nucleic acid (DNA or RNA); Babesia microti, amplified probe technique
  • 87478 – infectious agent detection by nucleic acid (DNA or RNA); Borrelia miyamotoi, amplified probe technique
  • 87484 – infectious agent detection by nucleic acid
  • 87913 – infectious agent genotype analysis by nucleic acid
  • 0285U – oncology, response to radiation
  • 0287U – oncology (thyroid), DNA and mRNA
  • 0288U – oncology (lung), mRNA, quantitative PCR analysis of 11 genes
  • 2091U – psychiatry (mood disorders)
  • 0292U – psychiatry (stress disorders)

Pathology CPT Modifiers

Modifiers are an important element in everyday medical billing practices. If modifiers are paired with the correct corresponding CPT codes, billing accuracy will improve and lower the chance of claim denials. Here are the recent updates for pathology modifiers in 2023:

  • 26 – professional component
  • 24 – surgery or postoperative visit
  • 88304 – benign diagnosis
  • 88305 – malignant
  • 310 – not vaccinated against COVID-19
  • 311 – partly vaccinated against COVID-19
  • 39 – indicates any other under-immunized status

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For informational purposes only.