Radiology CPT Codes and Modifiers for 2025

Radiology billing can get complicated quickly—between global vs. professional components, modality types, and contrast usage. To ensure accurate billing and full reimbursement, radiology practices and imaging centers must stay up to date on CPT codes and modifiers for 2025.

This guide outlines the most frequently used Radiology CPT codes, modifiers, and ICD-10 pairings, along with coding tips specific to diagnostic imaging and interventional procedures.

Common Diagnostic Imaging Codes

Interventional Radiology Procedures

Radiology Modifiers

Common ICD-10 Codes Used in Radiology

Radiology Coding Tips for 2025

• Use -26 or -TC unless billing globally for both components.
• Repeat studies? Use -76 (same provider) or -91 (diagnostic test repeat).
• Use -59 with caution—only for separate, distinct services.
• Use correct contrast code sequencing for CT and MRI exams.
• Screening vs. diagnostic? Choose ICD-10 codes carefully to reflect intent.

Final Thoughts

Radiology billing requires attention to both clinical and technical detail. With the right Radiology CPT codes and modifiers for 2025, your practice can avoid denials, pass audits, and collect the revenue you’ve earned—whether you’re reading images or running an imaging center.

For informational purposes only.